Benzenesulfonyl chloride, 3-(difluoromethoxy)- (9CI)

Benzenesulfonyl chloride, 3-(difluoromethoxy)- (9CI) - Names and Identifiers

Name	3-(Difluoromethoxy)benzenesulfonyl chloride
Synonyms	3-(DIFLUOROMETHOXY)BENZENESULFONYL CHLORIDE 3-(Difluoromethoxy)benzenesulfonyl chloride 3-(DIFLUOROMETHOXY)BENZENESULPHONYL CHLORIDE 3-(difluoromethoxy)benzene-1-sulfonyl chloride Benzenesulfonyl chloride, 3-(difluoromethoxy)- benzenesulfonyl chloride, 3-(difluoromethoxy)- Benzenesulfonyl chloride, 3-(difluoromethoxy)- (9CI)
CAS	351003-38-8
InChI	InChI=1/C7H5ClF2O3S/c8-14(11,12)6-3-1-2-5(4-6)13-7(9)10/h1-4,7H

Benzenesulfonyl chloride, 3-(difluoromethoxy)- (9CI) - Physico-chemical Properties

Molecular Formula	C7H5ClF2O3S
Molar Mass	242.63
Density	1.509 g/mL at 25 °C (lit.)
Boling Point	233-234 °C (lit.)
Flash Point	208°F
Solubility	Chloroform (Slightly), DMSO (Slightly)
Vapor Presure	0.00213mmHg at 25°C
Appearance	Oil
Color	Colourless to Pale Yellow
Storage Condition	2-8°C
Stability	Hygroscopic, Moisture Sensitive
Refractive Index	n20/D 1.5100(lit.)

Benzenesulfonyl chloride, 3-(difluoromethoxy)- (9CI) - Risk and Safety

Risk Codes	34 - Causes burns
Safety Description	S22 - Do not breathe dust. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	UN 3265 8/PG 2
WGK Germany	3
Hazard Note	Corrosive

Benzenesulfonyl chloride, 3-(difluoromethoxy)- (9CI) - Introduction

3-(Difluoromethoxy)benzenesulfonyl chloride is an organic compound with the chemical formula C7H4ClF2O3S. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 3-(Difluoromethoxy)benzenesulfonyl chloride is a colorless to light yellow solid.
-Solubility: It can be dissolved in common organic solvents such as ethanol, dimethyl sulfoxide and chlorinated hydrocarbons.
-Melting point: about 65-68 ℃.

Use:
- 3-(Difluoromethoxy)benzenesulfonyl chloride is often used as an important intermediate in organic synthesis and can be used to synthesize drugs, pesticides and other organic compounds.
-It can also be used for the synthesis of functional polymers, as well as reaction protective agents and fixing reagents in organic synthesis.

Preparation Method:
- 3-(Difluoromethoxy)benzenesulfonyl chloride is generally obtained by reacting benzenesulfonyl chloride with trifluoromethyl alcohol. The reaction conditions are generally carried out at a low temperature, and attention should be paid to safety.

Safety Information:
- 3-(Difluoromethoxy)benzenesulfonyl chloride is an organochlorine compound, which is irritating and corrosive. Personal protective equipment such as chemical goggles, protective gloves and laboratory coats are required for use.
-Avoid contact with skin, eyes and respiratory tract, avoid inhaling its vapors. Wash and dispose of waste thoroughly after use.
-Store away from fire and heat sources, and store in a dry and ventilated place.

Last Update：2024-04-09 02:00:45